Hot Topics - May 2011
The surprising link between gum disease and cancer - by Gerald P. Curatola, D.D.S.
Brushing and flossing, the universal mantra of dental professionals, is an essential habit for maintaining oral health. However, according to a growing body of scientific research, it may now become a prescription for saving your life.
For years, a link between gum disease and many systemic illnesses such as heart disease, diabetes and stroke has been well documented. In January 2007, a Harvard University School of Public Health study published in the Journal of the National Cancer Institute, uncovered a strong correlation of advanced gum disease in men to a 63% higher incidence of pancreatic cancer. A recent research report in the prestigious journal, Lancet Oncology, confirmed that cancer risk increases when gum disease is present. Even the presence of moderate gum disease contributed to an overall 14% increased risk of cancer. These include lung, kidney and blood cancers in both smokers and non-smokers.
A British and American research team at Imperial College in London and Harvard University studied the statistical health records of 50,000 patients from data collected over 21 years. There was a 33% increase in the risk of lung cancer, 50% rise in the risk of kidney cancer, and a 30% higher incidence of blood cancers, such as leukemia, among those with gum disease. Chronic advanced gum disease was the most frightening – with an additional fourfold increase in head and neck cancer for each millimeter of related bone loss around teeth.
While the precise cause of this correlation is the subject of extensive ongoing research, much attention is directed at the inflammation process, the oral biofilm, and the competency of the immune response.
When in balance (homeostasis), the oral biofilm, a complex community of billions of bacteria in the mouth, actually protect you and support your body’s ability to live. However, when disturbed, the oral biofilm produces pathogens (bad bacteria) that lead to gum disease. These bacteria can also get into your blood (circulatory system) and do nasty things. Pathogenic bacteria, and the toxins associated with them, place your immune system on alert (the inflammation process) and cause the liver to produce C-reactive proteins (CRP). CRP levels have inflammatory effects on arteries allowing these bacteria to attach themselves and form dangerous plaques inside the linings of these vessels.
In fact, gum disease has been identified as the body’s most abundant source of chronic low-grade inflammation which is described as “a smoldering fire in your body where the alarm bell is not answered.” This causes a decrease in the body’s immune response, and eventually, irreversible damage to the immune system, which is being identified as a likely factor for the increased cancer risk.
Gum disease is treatable and even reversible. Diligent attention to the formation of unhealthy (smelly, sticky) dental plaque, a sign of an unbalanced oral biofilm, should be regarded as the beginning of a process that can save your life and add years to your lifespan.
This article was taken from the Dr. Oz website
Brushing and flossing, the universal mantra of dental professionals, is an essential habit for maintaining oral health. However, according to a growing body of scientific research, it may now become a prescription for saving your life.
For years, a link between gum disease and many systemic illnesses such as heart disease, diabetes and stroke has been well documented. In January 2007, a Harvard University School of Public Health study published in the Journal of the National Cancer Institute, uncovered a strong correlation of advanced gum disease in men to a 63% higher incidence of pancreatic cancer. A recent research report in the prestigious journal, Lancet Oncology, confirmed that cancer risk increases when gum disease is present. Even the presence of moderate gum disease contributed to an overall 14% increased risk of cancer. These include lung, kidney and blood cancers in both smokers and non-smokers.
A British and American research team at Imperial College in London and Harvard University studied the statistical health records of 50,000 patients from data collected over 21 years. There was a 33% increase in the risk of lung cancer, 50% rise in the risk of kidney cancer, and a 30% higher incidence of blood cancers, such as leukemia, among those with gum disease. Chronic advanced gum disease was the most frightening – with an additional fourfold increase in head and neck cancer for each millimeter of related bone loss around teeth.
While the precise cause of this correlation is the subject of extensive ongoing research, much attention is directed at the inflammation process, the oral biofilm, and the competency of the immune response.
When in balance (homeostasis), the oral biofilm, a complex community of billions of bacteria in the mouth, actually protect you and support your body’s ability to live. However, when disturbed, the oral biofilm produces pathogens (bad bacteria) that lead to gum disease. These bacteria can also get into your blood (circulatory system) and do nasty things. Pathogenic bacteria, and the toxins associated with them, place your immune system on alert (the inflammation process) and cause the liver to produce C-reactive proteins (CRP). CRP levels have inflammatory effects on arteries allowing these bacteria to attach themselves and form dangerous plaques inside the linings of these vessels.
In fact, gum disease has been identified as the body’s most abundant source of chronic low-grade inflammation which is described as “a smoldering fire in your body where the alarm bell is not answered.” This causes a decrease in the body’s immune response, and eventually, irreversible damage to the immune system, which is being identified as a likely factor for the increased cancer risk.
Gum disease is treatable and even reversible. Diligent attention to the formation of unhealthy (smelly, sticky) dental plaque, a sign of an unbalanced oral biofilm, should be regarded as the beginning of a process that can save your life and add years to your lifespan.
This article was taken from the Dr. Oz website
